The Neurochemistry of Fairness Clarifying the Link between Serotonin and Prosocial Behavior

被引:56
作者
Crockett, Molly J. [1 ]
机构
[1] Univ Cambridge, Dept Expt Psychol, Behav & Clin Neurosci Inst, Cambridge CB2 3EB, England
来源
VALUES, EMPATHY, AND FAIRNESS ACROSS SOCIAL BARRIERS | 2009年 / 1167卷
基金
英国医学研究理事会; 英国惠康基金;
关键词
serotonin; fairness; neuroeconomics; aggression; prosocial behavior; ACUTE TRYPTOPHAN DEPLETION; PREFRONTAL CORTEX; DECISION-MAKING; CSF; 5-HIAA; SOCIOECONOMIC-STATUS; AGGRESSIVE-BEHAVIOR; CEREBROSPINAL-FLUID; HEALTHY-VOLUNTEERS; SOCIAL-BEHAVIOR; ULTIMATUM GAME;
D O I
10.1111/j.1749-6632.2009.04506.x
中图分类号
B84 [心理学];
学科分类号
04 ; 0402 ;
摘要
Decades of research have linked the neurotransmitter serotonin (5-HT) to prosocial behavior. However, the precise mechanisms through which 5-HT influences social interactions remain unclear. A neuroeconomics approach may help clarify these mechanisms. In a recent study, lowering 5-HT levels in healthy volunteers enhanced their reactions to unfair treatment in the ultimatum game. Other studies investigating the neural mechanisms of social decision making have implicated brain regions that are modulated by 5-HT. Here, I review the evidence for the role of 5-HT in modulating social decision making and discuss the implications for understanding how prosocial behavior varies between individuals and across social contexts.
引用
收藏
页码:76 / 86
页数:11
相关论文
共 96 条
[71]   DOMINANT SOCIAL-STATUS FACILITATES THE BEHAVIORAL-EFFECTS OF SEROTONERGIC AGONISTS [J].
RALEIGH, MJ ;
BRAMMER, GL ;
MCGUIRE, MT ;
YUWILER, A .
BRAIN RESEARCH, 1985, 348 (02) :274-282
[72]   SEROTONERGIC INFLUENCES ON THE SOCIAL-BEHAVIOR OF VERVET MONKEYS (CERCOPITHECUS-AETHIOPS-SABAEUS) [J].
RALEIGH, MJ ;
BRAMMER, GL ;
YUWILER, A ;
FLANNERY, JW ;
MCGUIRE, MT ;
GELLER, E .
EXPERIMENTAL NEUROLOGY, 1980, 68 (02) :322-334
[73]   Uncoupling of behavioral and autonomic responses after lesions of the primate orbitofrontal cortex [J].
Reekie, Y. L. ;
Braesicke, K. ;
Man, M. S. ;
Roberts, A. C. .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2008, 105 (28) :9787-9792
[74]   Shifting and stopping: fronto-striatal substrates, neurochemical modulation and clinical implications [J].
Robbins, T. W. .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2007, 362 (1481) :917-932
[75]   Chemical neuromodulation of frontal-executive functions in humans and other animals [J].
Robbins, TW .
EXPERIMENTAL BRAIN RESEARCH, 2000, 133 (01) :130-138
[76]   Synergistic and regulatory effects of orbitofrontal cortex on amygdala-dependent appetitive behavior [J].
Roberts, A. C. ;
Reekie, Y. ;
Braesicke, K. .
LINKING AFFECT TO ACTION: CRITICAL CONTRIBUTIONS OF THE ORBITOFRONTAL CORTEX, 2007, 1121 :297-319
[77]   Tryptophan depletion alters the decision-making of healthy volunteers through altered processing of reward cues [J].
Rogers, RD ;
Tunbridge, EM ;
Bhagwagar, Z ;
Drevets, WC ;
Sahakian, BJ ;
Carter, CS .
NEUROPSYCHOPHARMACOLOGY, 2003, 28 (01) :153-162
[78]   The effect of acute tryptophan depletion on the neural correlates of emotional processing in healthy volunteers [J].
Roiser, Jonathan P. ;
Levy, Jamey ;
Fromm, Stephen J. ;
Wang, Hongye ;
Hasler, Gregor ;
Sahakian, Barbara J. ;
Drevets, Wayne C. .
NEUROPSYCHOPHARMACOLOGY, 2008, 33 (08) :1992-2006
[79]   The neural basis of economic decision-making in the ultimatum game [J].
Sanfey, AG ;
Rilling, JK ;
Aronson, JA ;
Nystrom, LE ;
Cohen, JD .
SCIENCE, 2003, 300 (5626) :1755-1758
[80]   Introduction. Neuroeconomics: the promise and the profit [J].
Schultz, Wolfram .
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 2008, 363 (1511) :3767-3769