MapView: visualization of short reads alignment on a desktop computer

被引：58

作者：

Bao, Hua ^{[1
,2
]}

Guo, Hui ^{[1
,2
]}

Wang, Jinwei ^{[3
]}

Zhou, Renchao ^{[1
,2
]}

Lu, Xuemei ^{[1
,2
]}

Shi, Suhua ^{[1
,2
]}

机构：

[1] Sun Yat Sen Univ, Sch Life Sci, State Key Lab Biocontrol, Guangzhou 510275, Guangdong, Peoples R China

[2] Sun Yat Sen Univ, Sch Life Sci, Key Lab Gene Engn, Guangzhou 510275, Guangdong, Peoples R China

[3] Sichuan Univ, Sch Mfg Sci & Engn, Chengdu 610064, Peoples R China

来源：

BIOINFORMATICS | 2009年 / 25卷 / 12期

基金：

中国国家自然科学基金;

关键词：

GENOME;

D O I：

10.1093/bioinformatics/btp255

中图分类号：

Q5 [生物化学];

学科分类号：

070307 [化学生物学];

摘要：

We introduce a new visual analytics tool named MapView to facilitate the representation of large-scale short reads alignment data and genetic variation analysis. MapView can handle hundreds of millions of short reads on a desktop computer with limited memory. It supports a compact alignment view for both single-end and paired end short reads, multiple navigation and zoom modes and multi-thread processing. Moreover, MapView offers automated genetic variation detection. MapView has been used in our lab and by over 10 research labs worldwide.

引用

页码：1554 / 1555

页数：2

共 9 条

[1]

An SNP map of the human genome generated by reduced representation shotgun sequencing [J].