Monoamines and sleep: microdialysis findings in pons and amygdala

被引:74
作者
Shouse, MN
Staba, RJ
Saquib, SF
Farber, PR
机构
[1] Dept Vet Affairs, Greater Los Angeles Hlth Care Syst, Sepulveda, CA 91343 USA
[2] Univ Calif Los Angeles, Dept Neurobiol, Ctr Hlth Sci, Los Angeles, CA 90063 USA
关键词
monoamines; amygdala; locus ceruleus; microdialysis; sleep; cat;
D O I
10.1016/S0006-8993(00)02013-8
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
This is the first microdialysis report comparing concentrations (pg/mu l) of norepinephrine (NE), serotonin (5-HT) and dopamine (DA) derived from feline locus ceruleus complex (LC) and amygdala. NE and 5-HT declined progressively from waking to slow-wave-sleep (SWS) and then to rapid-eye-movement (REM) sleep. Concentrations of DA did not change at either collection site across the sleep-wake cycle. We conclude that release of NE and 5-HT release modulates physiologic components related to the sleep-wake cycle, but DA does not. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
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页码:181 / 189
页数:9
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