Neurodegeneration - A silent channel opens its gates

被引：5

作者：

Seeburg, PH

机构：

[1] Max Planck Institute for Medical Research,Department of Molecular Neuroscience

来源：

NATURE | 1997年 / 388卷 / 6644期

关键词：

D O I：

10.1038/41880

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Many human neurodegenerative disorders such as Alzheimer's disease and Parkinson's disease are caused by the death of specific populations of nerve cells. Using a strain of mutant mouse known aslurcher-- which has a peculiar gait caused by the loss of neurons in a brain structure that is important for motor coordination -- a new study has shown that cell death is due to a mutation in the δ2 subunit of the glutamate receptor.

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页码：716 / 717

页数：2

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