A pilot survey of sexual function and quality of life following 3D conformal radiotherapy for clinically localized prostate cancer

被引:45
作者
Roach, M
Chinn, DM
Holland, J
Clarke, M
机构
[1] UNIV CALIF SAN FRANCISCO,DEPT RADIAT ONCOL,SAN FRANCISCO,CA 94143
[2] UNIV CALIF SAN FRANCISCO,DEPT PSYCHIAT,SAN FRANCISCO,CA 94143
[3] OREGON HLTH SCI UNIV,DEPT RADIAT ONCOL,PORTLAND,OR 97201
来源
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 1996年 / 35卷 / 05期
关键词
prostate cancer; conformal radiation therapy; sexual dysfunction; impotence; quality of life;
D O I
10.1016/0360-3016(96)00206-4
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Purpose: To assess the impact of high dose three-dimensional conformal radiotherapy (3D CRT) for prostate cancer on the sexual function-related Quality of life of patients and their partners. Methods and Materials: Sixty of 124 consecutive patients (median age 72.3 years) treated with 3D CRT for localized prostate cancer were surveyed and reported being potent prior to treatment. The answers to survey questions assessing the impact of quality of life related to sexual function from these 60 patients and their partners forms the basis for this retrospective analysis. Results: Following 3D CRT, 37 of 60 patients (62%) retained sexual function sufficient for intercourse. Intercourse at least once per month was reduced from 71 to 40%, whereas intercourse less than once per year increased from 12 to 35%. Following treatment, 25% of patients reported that the change in sexual dysfunction negatively affected their relationship or resulted in poor self-esteem. This outcome was associated with impotence following treatment (p < 0.01). Patients who had partners and satisfactory sexual function appeared to be at a higher risk of having a negatively affected relationship or losing self-esteem if they become impotent (p < 0.05). Partners of patients who reported a negatively affected relationship or loss of self-esteem appear to be less likely to return the survey instrument used (p = 0.02). Conclusions: More work is needed to evaluate the impact of radiotherapy and other treatments on the quality of life of patients and their partners to allow adequate informed consent to be given.
引用
收藏
页码:869 / 874
页数:6
相关论文
共 29 条
  • [11] HANKS G E, 1988, NCI (National Cancer Institute) Monographs, P75
  • [12] DECREASED SEXUAL CAPACITY AFTER EXTERNAL RADIATION-THERAPY FOR PROSTATE-CANCER IMPAIRS QUALITY-OF-LIFE
    HELGASON, AR
    FREDERIKSON, M
    ADOLFSSON, J
    STEINECK, G
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1995, 32 (01): : 33 - 39
  • [13] LEIBEL SA, 1993, INT J RADIAT ONCOL, V28, P55
  • [14] QUALITY-OF-LIFE OUTCOMES IN MEN FOR LOCALIZED PROSTATE-CANCER
    LITWIN, MS
    HAYS, RD
    FINK, A
    GANZ, PA
    LEAKE, B
    LEACH, GE
    BROOK, RH
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1995, 273 (02): : 129 - 135
  • [15] A STUDY OF PENILE CIRCULATION BEFORE AND AFTER RADIATION IN PATIENTS WITH PROSTATE-CANCER AND ITS EFFECT ON IMPOTENCE
    MITTAL, B
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1985, 11 (06): : 1121 - 1125
  • [16] CLINICAL EXPERIENCE WITH SUPERVOLTAGE RADIOTHERAPY IN CARCINOMA OF PROSTATE - PRELIMINARY REPORT
    MOLLENKAMP, JS
    COOPER, JF
    KAGAN, AR
    [J]. JOURNAL OF UROLOGY, 1975, 113 (03) : 374 - 377
  • [17] TECHNICAL FACTORS AFFECTING MORBIDITY IN DEFINITIVE IRRADIATION FOR LOCALIZED CARCINOMA OF THE PROSTATE
    PEREZ, CA
    LEE, HK
    GEORGIOU, A
    LOCKETT, MA
    [J]. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1994, 28 (04): : 811 - 819
  • [18] PERLMAN CK, 1972, J UROLOGY, V107, P298
  • [19] SEXUALITY IN A 70-YEAR-OLD URBAN-POPULATION
    PERSSON, G
    [J]. JOURNAL OF PSYCHOSOMATIC RESEARCH, 1980, 24 (06) : 335 - 342
  • [20] DEFINITIVE RADIATION-THERAPY OF CARCINOMA OF PROSTATE - REPORT ON 15 YEARS OF EXPERIENCE
    RAY, GR
    CASSADY, JR
    BAGSHAW, MA
    [J]. RADIOLOGY, 1973, 106 (02) : 407 - 418