Impact of proteomics on bladder cancer research

被引：30

作者：

Celis, JE ^{[1
]}

Gromova, I ^{[1
]}

Moreira, JMA ^{[1
]}

Cabezón, T ^{[1
]}

Gromov, P ^{[1
]}

机构：

[1] Danish Canc Soc, Inst Canc Biol, DK-2100 Copenhagen O, Denmark

来源：

PHARMACOGENOMICS | 2004年 / 5卷 / 04期

关键词：

bladder cancer; early detection; premalignant lesions; protein profiles; therapeutic targets; translational research; tumor interstitial fluid; urine markers;

D O I：

10.1517/14622416.5.4.381

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

Detecting bladder cancer at an early stage and predicting how a tumor will behave and act in response to therapy, as well as the identification of new targets for therapeutic intervention, are among the main areas of research that will benefit from the current explosion in the number of powerful technologies emerging within proteomics. The purpose of this article is to briefly review what has been achieved to date using proteomic technologies and to bring forward novel strategies - based on the analysis of clinically relevant samples - that promise to accelerate the translation of basic discoveries into the daily clinical practice.

引用

页码：381 / 394

页数：14

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