Neural stimulation with a carbon nanotube microelectrode array

被引：315

作者：

Wang, Ke ^{[1
]}

Fishman, Harvey A.

Dai, Hongjie

Harris, James S.

机构：

[1] Stanford Univ, Dept Appl Phys, Stanford, CA 94305 USA

[2] Stanford Univ, Dept Chem, Stanford, CA 94305 USA

[3] Stanford Univ, Dept Ophthalmol, Stanford, CA 94305 USA

[4] Stanford Univ, Dept Elect Engn, Stanford, CA 94305 USA

来源：

NANO LETTERS | 2006年 / 6卷 / 09期

关键词：

D O I：

10.1021/nl061241t

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We present a novel prototype neural interface using vertically aligned multiwalled carbon nanotube ( CNT) pillars as microelectrodes. Functionalized hydrophilic CNT microelectrodes offer a high charge injection limit ( 1-1.6 mC/cm(2)) without faradic reactions. The first repeated in vitro stimulation of hippocampal neurons with CNT electrodes is demonstrated. These results suggest that CNTs are capable of providing far safer and more efficacious solutions for neural prostheses than previous metal electrode approaches.

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收藏

页码：2043 / 2048

页数：6

相关论文

共 31 条

[1]

Bard A.J, 2004, ELECTROCHEMICAL METH

[2] Electrochemical studies of single-wall carbon nanotubes in aqueous solutions [J].

Barisci, JN ;

Wallace, GG ;

Baughman, RH .

JOURNAL OF ELECTROANALYTICAL CHEMISTRY, 2000, 488 (02) :92-98

[3] Deep brain stimulation for Parkinson's disease [J].

Benabid, AL .

CURRENT OPINION IN NEUROBIOLOGY, 2003, 13 (06) :696-706

[4] OPTIMIZED SURVIVAL OF HIPPOCAMPAL-NEURONS IN B27-SUPPLEMENTED NEUROBASAL(TM), A NEW SERUM-FREE MEDIUM COMBINATION [J].

BREWER, GJ ;

TORRICELLI, JR ;

EVEGE, EK ;

PRICE, PJ .

JOURNAL OF NEUROSCIENCE RESEARCH, 1993, 35 (05) :567-576

[5] CRITERIA FOR SELECTING ELECTRODES FOR ELECTRICAL-STIMULATION - THEORETICAL AND PRACTICAL CONSIDERATIONS [J].

BRUMMER, SB ;

ROBBLEE, LS ;

HAMBRECHT, FT .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1983, 405 (JUN) :159-171

[6] ELECTROCHEMICAL CONSIDERATIONS FOR SAFE ELECTRICAL-STIMULATION OF NERVOUS-SYSTEM WITH PLATINUM-ELECTRODES [J].

BRUMMER, SB ;

TURNER, MJ .

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1977, 24 (01) :59-63

[7] Double-layer capacitance of carbide derived carbons in sulfuric acid [J].

Chmiola, J ;

Yushin, G ;

Dash, RK ;

Hoffman, EN ;

Fischer, JE ;

Barsoum, MW ;

Gogotsi, Y .

ELECTROCHEMICAL AND SOLID STATE LETTERS, 2005, 8 (07) :A357-A360

[8] Over-pulsing degrades activated iridium oxide films used for intracortical neural stimulation [J].

Cogan, SF ;

Guzelian, AA ;

Agnew, WF ;

Yuen, TGH ;

McCreery, DB .

JOURNAL OF NEUROSCIENCE METHODS, 2004, 137 (02) :141-150

[9] Bending and buckling of carbon nanotubes under large strain [J].

Falvo, MR ;

Clary, GJ ;

Taylor, RM ;

Chi, V ;

Brooks, FP ;

Washburn, S ;

Superfine, R .

NATURE, 1997, 389 (6651) :582-584

[10] Self-oriented regular arrays of carbon nanotubes and their field emission properties [J].

Fan, SS ;

Chapline, MG ;

Franklin, NR ;

Tombler, TW ;

Cassell, AM ;

Dai, HJ .

SCIENCE, 1999, 283 (5401) :512-514

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