Tau phosphorylation, aggregation, and cell toxicity

被引：45

作者：

Avila, J. ^{[1
]}

Santa-Maria, I. ^{[1
]}

Perez, M. ^{[1
]}

Hernandez, F. ^{[1
]}

Moreno, F. ^{[1
]}

机构：

[1] Univ Autonoma Madrid, Ctr Biol Mol Severo Ochoa, Fac Ciencias, E-28049 Madrid, Spain

来源：

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY | 2006年

关键词：

D O I：

10.1155/JBB/2006/74539

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];

摘要：

Protein aggregation takes place in many neurodegenerative disorders. However, there is a controversy about the possible toxicity of these protein aggregates. In this review, this controversy is discussed, focussing on the tau aggregation that takes place in those disorders known as tauopathies.

引用

页数：5

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