Microbial transformation of sclareolide

被引：29

作者：

AttaurRahman

Farooq, A

Choudhary, MI

机构：

[1] H. E. J. Res. Institute of Chemistry, University of Karachi

来源：

JOURNAL OF NATURAL PRODUCTS | 1997年 / 60卷 / 10期

关键词：

D O I：

10.1021/np970076h

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The microbial transformation of sclareolide (1) by Curvularia lunata afforded five oxidized metabolites identified as 3-ketosclareolide (2), 1 beta-hydroxysclareolide (3), 3 beta-hydroxysclareolide (4), 1 alpha,3 beta-dihydroxysclareolide (5), and 1 beta,3 beta-dihydroxysclareolide (6). Fermentations of 1 with Aspergillus niger also produced metabolites 2-6. Metabolites 2-5 were obtained by fermention with Gibberella fujikuroii, while fermentation with Fusarium lini afforded metabolites 4 and 5.

引用

页码：1038 / 1040

页数：3

共 8 条

[1] MICROBIAL TRANSFORMATION OF DITERPENES - HYDROXYLATION OF SCLAREOL, MANOOL AND DERIVATIVES BY MUCOR-PLUMBEUS [J].