Visualization of gene expression in living adult Drosophila

被引：423

作者：

Calleja, M ^{[1
]}

Moreno, E ^{[1
]}

Pelaz, S ^{[1
]}

Morata, G ^{[1
]}

机构：

[1] UNIV AUTONOMA MADRID, CSIC, CTR BIOL MOL, E-28049 MADRID, SPAIN

来源：

SCIENCE | 1996年 / 274卷 / 5285期

关键词：

D O I：

10.1126/science.274.5285.252

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

To identify genes involved in the patterning of adult structures, Ga14-UAS (upstream activating site) technology was used to visualize patterns of gene expression directly in living flies. A large number of Ga14 insertion lines were generated and their expression patterns were studied. In addition to identifying several characterized developmental genes, the approach revealed previously unsuspected genetic subdivisions of the thorax, which may control the disposition of pattern elements. The boundary between two of these domains coincides with localized expression of the signaling molecule wingless.

引用

页码：252 / 255

页数：4

共 38 条

[1]

ARIAS AM, 1988, DEVELOPMENT, V103, P157

[2] COMPARTMENT BOUNDARIES AND THE CONTROL OF DROSOPHILA LIMB PATTERN BY HEDGEHOG PROTEIN [J].

BASLER, K ;

STRUHL, G .

NATURE, 1994, 368 (6468) :208-214

[3]

BRAND A, 1994, METHOD CELL BIOL, P435

[4]

BRAND AH, 1993, DEVELOPMENT, V118, P401

[5]

CALLEJA M, UNPUB

[6] PATTERNING OF THE DROSOPHILA NERVOUS-SYSTEM - THE ACHAETE-SCUTE GENE-COMPLEX [J].

CAMPUZANO, S ;

MODOLELL, J .

TRENDS IN GENETICS, 1992, 8 (06) :202-208

[7] TARGETED EXPRESSION OF THE SIGNALING MOLECULE DECAPENTAPLEGIC INDUCES PATTERN DUPLICATIONS AND GROWTH ALTERATIONS IN DROSOPHILA WINGS [J].

CAPDEVILA, J ;

GUERRERO, I .

EMBO JOURNAL, 1994, 13 (19) :4459-4468

[8] PATTERN-FORMATION AND EYESPOT DETERMINATION IN BUTTERFLY WINGS [J].

CARROLL, SB ;

GATES, J ;

KEYS, DN ;

PADDOCK, SW ;

PANGANIBAN, GEF ;

SELEGUE, JE ;

WILLIAMS, JA .

SCIENCE, 1994, 265 (5168) :109-114

[9]

Cohen Stephen M., 1993, P747

[10]

DAMBLYCHAUDIERE C, 1992, INT J DEV BIOL, V36, P85

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