Effect at short-term vitamin (folic acid, vitamins B6 and B12) administration on endothelial dysfunction induced by post-methionine load hyperhomocysteinemia

被引：49

作者：

Chao, CL ^{[1
]}

Chien, KL ^{[1
]}

Lee, YT ^{[1
]}

机构：

[1] Natl Taiwan Univ Hosp, Dept Internal Med Cardiol, Coll Med, Taipei 10016, Taiwan

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1999年 / 84卷 / 11期

关键词：

D O I：

10.1016/S0002-9149(99)00575-5

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

This study showed that short-term vitamin administration effectively reduced post-methionine load homocysteine levels and thereby ameliorated endothelium-dependent flow-mediated vasodilation in 16 healthy adults. Post-methionine load homocysteine levels decreased from 22.7 +/- 3.8 to 17.0 +/- 2.1 mu mol/L (p <0.001), and flow-mediated vasodilation after methionine load increased from 8.6 +/- 3.6% to 13.8 +/- 2.9% (p <0.001) after vitamin administration.

引用

页码：1359 / +

页数：4

共 20 条

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