Danaparoid for cardiopulmonary bypass in patients with previous heparin-induced thrombocytopenia

被引：17

作者：

Gillis, S

Merin, G

Zahger, D

Deeb, M

Drenger, B

Hyam, E

Eldor, A

机构：

[1] HADASSAH UNIV HOSP,MED CTR,DEPT CARDIOTHORAC SURG,IL-91120 JERUSALEM,ISRAEL

[2] HADASSAH UNIV HOSP,MED CTR,DEPT ANAESTHESIOL,IL-91120 JERUSALEM,ISRAEL

[3] HADASSAH UNIV HOSP MT SCOPUS,CORONARY CARE UNIT,JERUSALEM,ISRAEL

[4] TEL AVIV MED CTR & SCH MED,HAEMATOL INST,TEL AVIV,ISRAEL

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 1997年 / 98卷 / 03期

关键词：

danaparoid; cardiopulmonary bypass; heparin; thrombocytopenia;

D O I：

10.1046/j.1365-2141.1997.2633080.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Anticoagulation for cardiopulmonary bypass in patients with heparin-induced thrombocytopenia requires the use of other anticoagulants, We report a case in whom this was achieved using the heparinoid danaparoid (Orgaran). Based on our experience and a review of the literature, we provide guidelines for managing these rare patients. A danaparoid dose substantially lower than that recommended by the manufacturer may minimize bleeding complications.

引用

页码：657 / 659

页数：3

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