Encapsulation of quantum nanodots in polystyrene and silica micro-/nanoparticles

被引:98
作者
Yang, XT
Zhang, Y
机构
[1] Natl Univ Singapore, Fac Engn, Div Bioengn, Singapore 117576, Singapore
[2] Natl Univ Singapore, Nanosci & Nanotechnol Initiat, Singapore 117576, Singapore
关键词
D O I
10.1021/la049610t
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The polystyrene particles of controlled sizes on both micro- and nanolevels and incorporate quantum dots (QD) into nanoparticle were synthesized. Silica particles coatings were made on polystyrene particles encapsulating QDs to provide another suitable surface for conjuction of biomolecules. It was found that the encapsulation of QDs solve the problems associated with QDs such as biocompatibility and stability. The results show that the encapsulation of QDs in polystyrene particles grafted with carboxyl groups were subsequently coated with a thin layer of silica to form core-shell structure.
引用
收藏
页码:6071 / 6073
页数:3
相关论文
共 18 条
[1]   Production of micron-sized polystyrene particles containing PEG near the particles surface [J].
Ahmad, H ;
Tauer, K .
COLLOID AND POLYMER SCIENCE, 2003, 281 (05) :476-484
[3]   Multilayered titania, silica, and Laponite nanoparticle coatings on polystyrene colloidal templates and resulting inorganic hollow spheres [J].
Caruso, RA ;
Susha, A ;
Caruso, F .
CHEMISTRY OF MATERIALS, 2001, 13 (02) :400-409
[4]   Luminescent quantum dots for multiplexed biological detection and imaging [J].
Chan, WCW ;
Maxwell, DJ ;
Gao, XH ;
Bailey, RE ;
Han, MY ;
Nie, SM .
CURRENT OPINION IN BIOTECHNOLOGY, 2002, 13 (01) :40-46
[5]   Quantum dot bioconjugates for ultrasensitive nonisotopic detection [J].
Chan, WCW ;
Nie, SM .
SCIENCE, 1998, 281 (5385) :2016-2018
[6]   Luminescent CdSe quantum dot doped stabilized micelles [J].
Chen, YF ;
Rosenzweig, Z .
NANO LETTERS, 2002, 2 (11) :1299-1302
[7]   Synthesis and properties of biocompatible water-soluble silica-coated CdSe/ZnS semiconductor quantum dots [J].
Gerion, D ;
Pinaud, F ;
Williams, SC ;
Parak, WJ ;
Zanchet, D ;
Weiss, S ;
Alivisatos, AP .
JOURNAL OF PHYSICAL CHEMISTRY B, 2001, 105 (37) :8861-8871
[8]   Avidin: A natural bridge for quantum dot-antibody conjugates [J].
Goldman, ER ;
Balighian, ED ;
Mattoussi, H ;
Kuno, MK ;
Mauro, JM ;
Tran, PT ;
Anderson, GP .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (22) :6378-6382
[9]   Quantum-dot-tagged microbeads for multiplexed optical coding of biomolecules [J].
Han, MY ;
Gao, XH ;
Su, JZ ;
Nie, S .
NATURE BIOTECHNOLOGY, 2001, 19 (07) :631-635
[10]   Layered paving of vesicular nanoparticles formed with cerasome as a bioinspired organic-inorganic hybrid [J].
Katagiri, K ;
Hamasaki, R ;
Ariga, K ;
Kikuchi, J .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2002, 124 (27) :7892-7893