A biochip based on magnetoresistive sensors

被引：71

作者：

Schotter, J ^{[1
]}

Kamp, PB

Becker, A

Pühler, A

Brinkmann, D

Schepper, W

Brückl, H

Reiss, G

机构：

[1] Univ Bielefeld, Dept Phys, D-33615 Bielefeld, Germany

[2] Univ Bielefeld, Dept Biol, D-33615 Bielefeld, Germany

来源：

IEEE TRANSACTIONS ON MAGNETICS | 2002年 / 38卷 / 05期

关键词：

bioniagneties; biomedical measurements; magnetoresistive devices; sensors;

D O I：

10.1109/TMAG.2002.802290

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

The signal response of Bangs Laboratories magnetic markers with a mean diameter of 0.86 mum on a spiral-shaped giant magnetoresistance sensor with a diameter of 70 mum is investigated. The data show a linear dependence of the sensor signal on the surface coverage of the magnetic markers. The detection limit is reached at a coverage of about 5%, which corresponds to about 200 markers distributed across the surface of the sensor. The corresponding molecular binding of the analyte DNA and the magnetic markers show good selectivity and sensitivity.

引用

页码：3365 / 3367

页数：3

共 8 条

[1] GIANT MAGNETORESISTANCE OF (001)FE/(001) CR MAGNETIC SUPERLATTICES [J].

BAIBICH, MN ;

BROTO, JM ;

FERT, A ;

VANDAU, FN ;

PETROFF, F ;

EITENNE, P ;

CREUZET, G ;

FRIEDERICH, A ;

CHAZELAS, J .

PHYSICAL REVIEW LETTERS, 1988, 61 (21) :2472-2475

[2]

*BANGS LAB INC, PROD CM01N 4620 CM01

[3] A biosensor based on magnetoresistance technology [J].

Baselt, DR ;

Lee, GU ;

Natesan, M ;

Metzger, SW ;

Sheehan, PE ;

Colton, RJ .

BIOSENSORS & BIOELECTRONICS, 1998, 13 (7-8) :731-739

[4]

GRAHAM DL, IN PRESS J APPL PHYS

[5]

Jackson J.D., 2001, Classical Electrodynmaics, VThird

[6] A DNA array sensor utilizing magnetic microbeads and magnetoelectronic detection [J].

Miller, MM ;

Sheehan, PE ;

Edelstein, RL ;

Tamanaha, CR ;

Zhong, L ;

Bounnak, S ;

Whitman, LJ ;

Colton, RJ .

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS, 2001, 225 (1-2) :138-144

[7] LARGE MAGNETORESISTANCE AT ROOM-TEMPERATURE IN FERROMAGNETIC THIN-FILM TUNNEL-JUNCTIONS [J].

MOODERA, JS ;

KINDER, LR ;

WONG, TM ;

MESERVEY, R .

PHYSICAL REVIEW LETTERS, 1995, 74 (16) :3273-3276

[8] Model for detection of immobilized superparamagnetic nanosphere assay labels using giant magnetoresistive sensors [J].

Tondra, M ;

Porter, M ;

Lipert, RJ .

JOURNAL OF VACUUM SCIENCE & TECHNOLOGY A-VACUUM SURFACES AND FILMS, 2000, 18 (04) :1125-1129

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