Alkaloids-catalyzed regio- and enantioselective allylic nucleophilic substitution of tert-butyl carbonate of the Morita-Baylis-Hillman products

被引：122

作者：

Du, YS ^{[1
]}

Han, XL ^{[1
]}

Lu, XY ^{[1
]}

机构：

[1] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 25期

基金：

中国国家自然科学基金;

关键词：

D O I：

10.1016/j.tetlet.2004.04.135

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The alkaloids-catalyzed regio- and enantioselective allylic nucleophilic substitution reactions of tert-butyl carbonate of the Morita-Baylis-Hillman products with pronucleophiles are reported. A number of pronucleophiles, such as nitrogen, oxygen, and active carbon pronucleophiles have been used in this facile reaction. In general, the reaction proceeded efficiently to give the Substitution product in good yields with high regioselectivity and medium enantioselectivity. (C) 2004 Elsevier Ltd. All rights reserved.

引用

页码：4967 / 4971

页数：5

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