Interactions between malaria and HIV infection - an emerging public health problem?

被引:18
作者
Rowland-Jones, SL [1 ]
Lohman, B
机构
[1] John Radcliffe Hosp, Weatherall Inst Mol Med, MRC, Human Immunol Unit, Oxford OX3 0DW, England
[2] Univ Nairobi, Dept Med Microbiol Annexe, Nairobi, Kenya
基金
英国医学研究理事会;
关键词
HIV-1; infection; malaria; pregnancy;
D O I
10.1016/S1286-4579(02)01655-6
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Recent evidence demonstrates interactions between malaria and HIV infection. HIV-infected people are more likely to experience clinical malaria, and acute malaria can up-regulate HIV replication, leading to higher plasma viral loads. This is most serious in pregnant women, where HIV infection increases the risk of placental malaria, leading to increased infant morbidity and mortality. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
引用
收藏
页码:1265 / 1270
页数:6
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