Potential antiamoebic property of the roots of Piper longum Linn

被引:22
作者
Ghoshal, S [1 ]
Lakshmi, V
机构
[1] Cent Drug Res Inst, Div Microbiol, Lucknow 226001, Uttar Pradesh, India
[2] Cent Drug Res Inst, Div Med Chem, Lucknow 226001, Uttar Pradesh, India
关键词
Entamoeba histolytica; Piper longum; antiamoebic; amoebiasis;
D O I
10.1002/ptr.1014
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
In an earlier study we reported the effect of ethanol extracts of Piper longum fruit against caecal amoebiasis in rats. A follow-up study to determine whether the roots possess similar antiamoebic activity was carried out. The ethanolic extract of roots was amoebicidal at 1000 mug/mL in vitro and cured 88% of caecal amoebiasis cases, suggesting that both the root and fruit of P. longum possess antiamoebic activity to approximately the same extent. Copyright (C) 2002 John Wiley Sons, Ltd.
引用
收藏
页码:689 / 691
页数:3
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