COPD - Exacerbation

被引:21
作者
Voelkel, NF
Tuder, R
机构
[1] Univ Colorado, Hlth Sci Ctr, Div Pulm Sci & Crit Care Med, Denver, CO 80262 USA
[2] Univ Colorado, Hlth Sci Ctr, Dept Pathol, Denver, CO 80262 USA
关键词
COPD; definition; exacerbation;
D O I
10.1378/chest.117.5_suppl_2.376S
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
A renewed interest in the clinical and pathogenic aspects of COPD exacerbation is timely in view of national and global COPD initiatives. The three big problems regarding COPD continue to be the following: prevention of the disease; slowing progression of the disease once diagnosis has been established; and prevention and more effective treatment of the so-called exacerbation. The following assessment will raise more questions than answers and will review some of the past and current concepts and contexts.
引用
收藏
页码:376S / 379S
页数:4
相关论文
共 33 条
[1]  
ALBERT RK, 1980, ANN INTERN MED, V92, P753, DOI 10.7326/0003-4819-92-6-753
[2]  
*AM THOR SOC, 1995, AM J RESP CRIT CARE, V152, pS78, DOI [10.1164/ajrccm/152.5_Pt_2.S78, DOI 10.1164/AJRCCM/152.5_PT_2.S78]
[3]  
[Anonymous], ERS MONOGRAPH
[4]   ANTIBIOTIC-THERAPY IN EXACERBATIONS OF CHRONIC OBSTRUCTIVE PULMONARY-DISEASE [J].
ANTHONISEN, NR ;
MANFREDA, J ;
WARREN, CPW ;
HERSHFIELD, ES ;
HARDING, GKM ;
NELSON, NA .
ANNALS OF INTERNAL MEDICINE, 1987, 106 (02) :196-204
[5]   Mechanisms of worsening gas exchange during acute exacerbations of chronic obstructive pulmonary disease [J].
Barbera, JA ;
Roca, J ;
Ferrer, A ;
Felez, MA ;
Diaz, O ;
Roger, N ;
RodriguezRoisin, R .
EUROPEAN RESPIRATORY JOURNAL, 1997, 10 (06) :1285-1291
[6]   Strategies for novel COPD therapies [J].
Barnes, PJ .
PULMONARY PHARMACOLOGY & THERAPEUTICS, 1999, 12 (02) :67-71
[7]   ACUTE RESPIRATORY-FAILURE IN CHRONIC OBSTRUCTIVE PULMONARY-DISEASE - IMMEDIATE AND LONG-TERM PROGNOSIS [J].
BURK, RH ;
GEORGE, RB .
ARCHIVES OF INTERNAL MEDICINE, 1973, 132 (06) :865-868
[8]   Value of C-reactive protein measurements in exacerbations of chronic obstructive pulmonary disease [J].
Dev, D ;
Wallace, E ;
Sankaran, R ;
Cunniffe, J ;
Govan, JRW ;
Wathen, CG ;
Emmanuel, FXS .
RESPIRATORY MEDICINE, 1998, 92 (04) :664-667
[9]   Severity of airflow limitation is associated with severity of airway inflammation in smokers [J].
Di Stefano, A ;
Capelli, A ;
Lusuardi, M ;
Balbo, P ;
Vecchio, C ;
Maestrelli, P ;
Mapp, CE ;
Fabbri, LM ;
Donner, CF ;
Saetta, M .
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 1998, 158 (04) :1277-1285
[10]   PILOT STUDY OF FACTORS ASSOCIATED WITH EXACERBATIONS IN CHRONIC BRONCHITIS [J].
FISHER, M ;
AKHTAR, AJ ;
CALDER, MA ;
MOFFAT, MAJ ;
STEWART, SM ;
ZEALLEY, H ;
CROFTON, JW .
BMJ-BRITISH MEDICAL JOURNAL, 1969, 4 (5677) :187-+