Nanostructured niobium oxide coatings influence osteoblast adhesion

被引：85

作者：

Eisenbarth, E. ^{[1
]}

Velten, D.

Mueller, M.

Thull, R.

Breme, J.

机构：

[1] Hamburg Univ Technol TUHH, Hamburg, Germany

[2] Univ Saarland, Lehrstuhl Met Werkstoffe, D-6600 Saarbrucken, Germany

[3] Univ Wurzburg, Funkt Werkstoffe Med & Zahnmed, Wurzburg, Germany

来源：

JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A | 2006年 / 79A卷 / 01期

关键词：

osteoblast; surface structure; adhesion; bone remodeling; bone ingrowth;

D O I：

10.1002/jbm.a.30823

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 [生物医学工程];

摘要：

The interaction of osteoblasts was correlated to the roughness of nanosized surface structures of Nb2O5 coatings on polished CP titanium grade 2. Nb2O5 sol-gel coatings were selected as a model surface to study the interaction of osteoblasts with nanosized surface structures. The surface roughness was quantified by determination of the average surface finish (Ra number) by means of atomic force microscopy. Surface topographies with Ra 7, 15, and 40 nm were adjusted by means of the annealing process parameters (time and temperature) within a sol-gel coating procedure. The observed osteoblast migration

引用

收藏

页码：166 / 175

页数：10

相关论文

共 33 条

[1]

Ambrosio L, 2004, Med J Malaysia, V59 Suppl B, P71

[2]

Activation of integrin function by nanopatterned adhesive interfaces [J].

Arnold, M ;

Cavalcanti-Adam, EA ;

Glass, R ;

Blümmel, J ;

Eck, W ;

Kantlehner, M ;

Kessler, H ;

Spatz, JP .

CHEMPHYSCHEM, 2004, 5 (03) :383-388

[3]

Adhesion-dependent cell mechanosensitivity [J].

Bershadsky, AD ;

Balaban, NQ ;

Geiger, B .

ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY, 2003, 19 :677-695

[4]

Osteoblast-mediated mineral deposition in culture is dependent on surface microtopography [J].

Boyan, BD ;

Bonewald, LF ;

Paschalis, EP ;

Lohmann, CH ;

Rosser, J ;

Cochran, DL ;

Dean, DD ;

Schwartz, Z ;

Boskey, AL .

CALCIFIED TISSUE INTERNATIONAL, 2002, 71 (06) :519-529

[5]

Mechanisms involved in osteoblast response to implant surface morphology [J].

Boyan, BD ;

Lohmann, CH ;

Dean, DD ;

Sylvia, VL ;

Cochran, DL ;

Schwartz, Z .

ANNUAL REVIEW OF MATERIALS RESEARCH, 2001, 31 :357-371

[6]

Endothelization and adherence of leucocytes to nanostructured surfaces [J].

Buttiglieri, S ;

Pasqui, D ;

Migliori, M ;

Johnstone, H ;

Affrossman, S ;

Sereni, L ;

Wratten, ML ;

Barbucci, R ;

Tetta, C ;

Camussi, G .

BIOMATERIALS, 2003, 24 (16) :2731-2738

[7]

Cells react to nanoscale order and symmetry in their surroundings [J].

Curtis, ASG ;

Gadegaard, N ;

Dalby, MJ ;

Riehle, MO ;

Wilkinson, CDW ;

Aitchison, G .

IEEE TRANSACTIONS ON NANOBIOSCIENCE, 2004, 3 (01) :61-65

[8]

Substratum nanotopography and the adhesion of biological cells. Are symmetry or regularity of nanotopography important? [J].

Curtis, ASG ;

Casey, B ;

Gallagher, JO ;

Pasqui, D ;

Wood, MA ;

Wilkinson, CDW .

BIOPHYSICAL CHEMISTRY, 2001, 94 (03) :275-283

[9]

Use of nanotopography to study mechanotransduction in fibroblasts - methods and perspectives [J].

Dalby, MJ ;

Riehle, MO ;

Sutherland, DS ;

Agheli, H ;

Curtis, ASG .

EUROPEAN JOURNAL OF CELL BIOLOGY, 2004, 83 (04) :159-169

[10]

Imaging the traction stresses exerted by locomoting cells with the elastic substratum method [J].

Dembo, M ;

Oliver, T ;

Ishihara, A ;

Jacobson, K .

BIOPHYSICAL JOURNAL, 1996, 70 (04) :2008-2022

← 1 2 3 4 →