Ovarian tissue cryopreservation and transplantation: a review

被引:337
作者
Donnez, Jacques [1 ]
Martinez-Madrid, Belen [1 ]
Jadoul, Pascale [1 ]
Van Langendonckt, Anne [1 ]
Demylle, Dominique [1 ]
Dolmans, Marie-Madeleine [1 ]
机构
[1] Catholic Univ Louvain, Dept Gynecol, B-1200 Brussels, Belgium
关键词
fertility preservation; ovarian tissue cryopreservation; transplantation;
D O I
10.1093/humupd/dml032
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
The review covers current options for ovarian tissue cryopreservation and transplantation and provides a systematic review of the existing literature from the last 10 years, taking into account all previously published reviews on the subject. The different cryopreservation options available for fertility preservation in cancer patients are embryo cryopreservation, oocyte cryopreservation and ovarian tissue cryopreservation. The choice depends on various parameters: the type and timing of chemotherapy, the type of cancer, the patient's age and the partner status. The different options and their results are discussed, as well as their putative indications and efficacy. The review concludes that advances in reproductive technology have made fertility preservation techniques a real possibility for patients whose gonadal function is threatened by premature menopause, or by treatments such as radiotherapy, chemotherapy or surgical castration.
引用
收藏
页码:519 / 535
页数:17
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