Synthesis and trimethylaluminum additions on γ-hydroxy-δ-sulfinyl and sulfonyl enoates

被引：9

作者：

Carreño, MC

Sanz-Cuestat, MJ

Colobert, F

Solladié, G

机构：

[1] Univ Autonoma Madrid, Fac Ciencias, Dept Quim Organ, E-28049 Madrid, Spain

[2] Univ Strasbourg, Lab Stereochim Associe, CNRS, ECPM, F-67087 Strasbourg 2, France

来源：

ORGANIC LETTERS | 2004年 / 6卷 / 20期

关键词：

D O I：

10.1021/ol048577z

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The stereoselective synthesis of epimeric (R)- and (S)-gamma-hydroxy-delta-p-tolylsulfinyl (or sulfonyl) enoates is reported. Reaction with AlMe3 occurred exclusively at the ester goup allowing a clean and high-yielding access to enantiopure 1,4-diols bearing a tertiary carbinol.

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页码：3537 / 3540

页数：4

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