The Biginelli condensation:: A novel and efficient regioselective synthesis of dihydropyrimidin-2(1H)-ones using lithium bromide

被引：40

作者：

Baruah, PP ^{[1
]}

Gadhwal, S ^{[1
]}

Prajapati, D ^{[1
]}

Sandhu, JS ^{[1
]}

机构：

[1] Reg Res Lab, Jorhat 785006, Assam, India

来源：

CHEMISTRY LETTERS | 2002年 / 10期

关键词：

D O I：

10.1246/cl.2002.1038

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Various substituted 3,4-dihydropyrimidin-2(1H)-ones were synthesised in one-pot reaction of aldehydes, beta-ketoesters and urea using LiBr in tetrahydrofuran in excellent yields without any side reactions as observed by Biginelli and others.

引用

页码：1038 / 1039

页数：2

共 22 条

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