Probiotics and prevention of necrotizing enterocolitis

被引：28

作者：

Mshvildadze, Maka ^{[1
,2
]}

Neu, Josef ^{[1
]}

机构：

[1] Univ Florida, Dept Pediat, Gainesville, FL 32610 USA

[2] Chachava Sci Res Inst Perinatal Med Obstet & Gyne, Tbilisi, Georgia

来源：

EARLY HUMAN DEVELOPMENT | 2009年 / 85卷 / 10期

关键词：

Microbiota; Microbiome; Probiotics; Prebiotics intestine; Premature infant; Necrotizing enterocolitis; LOW-BIRTH-WEIGHT; INDUCED INTERLEUKIN-8 PRODUCTION; TOLL-LIKE RECEPTORS; KAPPA-B; PREBIOTIC SUPPLEMENTATION; PRETERM INFANTS; DOUBLE-BLIND; GUT; REDUCE; TRANSLOCATION;

D O I：

10.1016/j.earlhumdev.2009.08.021

中图分类号：

R71 [妇产科学];

学科分类号：

100211 [妇产科学];

摘要：

Necrotizing enterocolitis (NEC) is a devastating disease affecting primarily premature infants. Despite advances in neonatal care, the mortality rate following NEC has not changed significantly in the past 30 years. New preventative measures are needed. In this review, we will provide information to assess the possible role of probiotics, prebiotics and related agents in the prevention of this devastating disease. We will also discuss short and long term safety issues as well as potential alternatives. Although it is tempting to rebuild the intestinal microbiota using the agents such as pro and prebiotics during infancy, routine use is not yet warranted a cautious approach on the basis of sounds scientific data is needed. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

引用

页码：S71 / S74

页数：4

共 45 条

[1]

Probiotics for prevention of necrotizing enterocolitis in preterm infants [J].

AlFaleh, K. ;

Bassler, D. .

COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2008, (01)

[2]

Probiotics for necrotizing enterocolitis: A systematic review [J].

Barclay, Andrew R. ;

Stenson, Ben ;

Simpson, Judith H. ;

Weaver, Lawrence T. ;

Wilson, David C. .

JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 2007, 45 (05) :569-576

[3]

Supplementation with galactooligosaccharides and inulin increases bacterial translocation in artifically reared newborn rats [J].

Barrat, Emmanuel ;

Michel, Catherine ;

Poupeau, Guillaume ;

David-Sochard, Agnes ;

Rival, Martine ;

Pagniez, Anthony ;

Champ, Martine ;

Darmaun, Dominique .

PEDIATRIC RESEARCH, 2008, 64 (01) :34-39

[4]

Oral probiotics prevent necrotizing enterocolitis in very low birth weight neonates [J].

Bin-Nun, A ;

Bromiker, R ;

Wilschanski, M ;

Kaplan, M ;

Rudensky, B ;

Caplan, M ;

Hammerman, C .

JOURNAL OF PEDIATRICS, 2005, 147 (02) :192-196

[5]

Boehm G., 2003, Functional dairy products, P203, DOI 10.1533/9781855736917.2.203

[6]

Supplementation of a bovine milk formula with an oligosaccharide mixture increases counts of faecal bifidobacteria in preterm infants [J].

Boehm, G ;

Lidestri, M ;

Casetta, P ;

Jelinek, J ;

Negretti, F ;

Stahl, B ;

Marini, A .

ARCHIVES OF DISEASE IN CHILDHOOD-FETAL AND NEONATAL EDITION, 2002, 86 (03) :178-181

[7]

BOYLE RJ, 2003, COCHRANE DB SYST REV

[8]

Probiotic use in clinical practice: what are the risks? [J].

Boyle, Robert J. ;

Robins-Browne, Roy M. ;

Tang, Mimi L. K. .

AMERICAN JOURNAL OF CLINICAL NUTRITION, 2006, 83 (06) :1256-1264

[9]

Probiotic and prebiotic supplementation for the prevention of neonatal necrotizing enterocolitis [J].

Caplan, M. S. .

JOURNAL OF PERINATOLOGY, 2009, 29 :S2-S6

[10]

Developmentally regulated IκB expression in intestinal epithelium and susceptibility to flagellin-induced inflammation [J].

Claud, EC ;

Lu, L ;

Anton, PM ;

Savidge, T ;

Walker, WA ;

Cherayil, BJ .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (19) :7404-7408

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