Community ecology as a framework for human microbiome research

被引：109

作者：

Gilbert, Jack A. ^{[1
,2
]}

Lynch, Susan V. ^{[3
]}

机构：

[1] Univ Calif San Diego, Dept Pediat, La Jolla, CA 92093 USA

[2] Univ Calif San Diego, Scripps Inst Oceanog, La Jolla, CA 92093 USA

[3] Univ Calif San Francisco, Dept Med, Div Gastroenterol, San Francisco, CA 94143 USA

来源：

NATURE MEDICINE | 2019年 / 25卷 / 06期

基金：

美国国家卫生研究院;

关键词：

HUMAN GUT MICROBIOME; COLONIZATION RESISTANCE; CLOSTRIDIUM-DIFFICILE; HOST; PROBIOTICS; EVOLUTION; INFECTION; ECOSYSTEM; IMPACTS; INFANTS;

D O I：

10.1038/s41591-019-0464-9

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

The field of human microbiome research has revealed the intimate co-association of humans with diverse communities of microbes in various habitats in the human body, and the necessity of these microbes for the maintenance of human health. Microbial heterogeneity between humans and across spatial and temporal gradients requires multidimensional datasets and a unifying set of theories and statistical tools to analyze the human microbiome and fully realize the potential of this field. Here we consider the utility of community ecology as a framework for the interrogation and interpretation of the human microbiome.

引用

页码：884 / 889

页数：6

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