The global regulator CsrA of Escherichia coli is a specific mRNA-binding protein

被引：142

作者：

Liu, MY

Romeo, T

机构：

[1] UNIV N TEXAS,HLTH SCI CTR,DEPT IMMUNOL & MICROBIOL,FT WORTH,TX 76107

[2] UNIV N TEXAS,HLTH SCI CTR,DEPT BIOCHEM & MOL BIOL,FT WORTH,TX

来源：

JOURNAL OF BACTERIOLOGY | 1997年 / 179卷 / 14期

关键词：

D O I：

10.1128/jb.179.14.4639-4642.1997

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The csrA gene encodes a global regulatory protein which facilitates glgC mRNA decay in vivo. A purified recombinant CsrA protein was found to inhibit in vitro glg (glycogen biosynthesis) gene expression posttranscriptionally and bind specifically to a glgC runoff transcript without causing its decay. Our results provide further insight into the mechanism by which CsrA functions as an mRNA decay factor.

引用

页码：4639 / 4642

页数：4

共 21 条

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