New terpenoids from the brown alga Stypopodium zonale

被引：19

作者：

Dorta, E ^{[1
]}

Cueto, M ^{[1
]}

Brito, I ^{[1
]}

Darias, J ^{[1
]}

机构：

[1] CSIC, Inst Prod Nat & Agrobiol, Tenerife 38206, Spain

来源：

JOURNAL OF NATURAL PRODUCTS | 2002年 / 65卷 / 11期

关键词：

D O I：

10.1021/np020090g

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Three new terpenoids, 1a-3a, and the known metabolites atomaric acid, stypoquinonic acid, and 5'a-desmethyl-5'-acetylatomaric acid have been isolated from the tropical brown alga Stypopodium zonale. The structures and relative stereochemistry of the methyl ester of 1a-3a were determined by spectral methods. The methyl ester of 3a exhibits in vitro cytotoxic activity against human lung and colon carcinoma.

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页码：1727 / 1730

页数：4

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