Invasion and intracellular trafficking of Brucella abortus in nonphagocytic cells

被引：56

作者：

Pizarro-Cerdá, J

Moreno, E

Gorvel, JP

机构：

[1] Inst Pasteur, Dept Bacteriol, Unite Interact Bacteries Cellules, F-75724 Paris 15, France

[2] Natl Univ, Sch Vet Med, Res Program Trop Dis, Heredia, Costa Rica

[3] CNRS Marseille Luminy, INSERM, Ctr Immunol, F-13288 Marseille 9, France

来源：

MICROBES AND INFECTION | 2000年 / 2卷 / 07期

关键词：

Brucella; intracellular trafficking; autophagocytosis; endoplasmic reticulum;

D O I：

10.1016/S1286-4579(00)90368-X

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Brucella abortus is a facultative intracellular parasite that promotes its own internalization in nonphagocytic cells. The bacterium initially interacts with compartments of the early endocytic cascade, then rapidly segregates from this intracellular pathway and associates with the autophagocytic cascade. During the late stages of infection, Brucella proliferates within the endoplasmic reticulum of host cells. (C) 2000 Editions scientifiques et medicales Elsevier SAS.

引用

页码：829 / 835

页数：7