A Review of Topical Hemostatic Agents for Use in Cardiac Surgery

被引:92
作者
Barnard, James [1 ]
Millner, Russell [1 ]
机构
[1] Blackpool Victoria Hosp, Dept Cardiothorac Surg, Lancashire Cardiac Ctr, Blackpool FY3 8NR, England
关键词
FIBRIN SEALANT; MICROFIBRILLAR COLLAGEN; ABSORBABLE CYANOACRYLATE; OXIDIZED CELLULOSE; BOVINE THROMBIN; CLINICAL-TRIAL; AORTIC-VALVE; CHITOSAN; BYPASS; TISSUE;
D O I
10.1016/j.athoracsur.2009.02.092
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Postoperative hemorrhage, redo sternotomy for bleeding, and transfusion of blood products are all associated with poorer outcomes in cardiac surgery. Topical hemostatic agents are important adjuncts to reduce blood loss after cardiac surgery and can have a role in reducing both "surgical" and "nonsurgical bleeding." There are many topical hemostatic agents to choose from, and with several new products in this field being approved for use in the last few years, the aim of this review is to appraise these agents and to look at the evidence for their efficacy. (Ann Thorac Surg 2009; 88: 1377-83) (C) 2009 by The Society of Thoracic Surgeons
引用
收藏
页码:1377 / 1383
页数:7
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