Cancer genetics: from Boveri and Mendel to microarrays

被引:70
作者
Balmain, A [1 ]
机构
[1] Univ Calif San Francisco, Canc Res Inst, San Francisco, CA 94143 USA
关键词
D O I
10.1038/35094086
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The human genome has now been sequenced, a century after the rediscovery of Mendel's Laws, and the publication of Theodor Boveri's chromosomal theory of heredity. Tracing the historical landmarks of cancer genetics from these early days to the present time not only gives us an appreciation of how far we have come, but also emphasizes the challenges that we face if we are to unravel the genetic basis of hereditary and sporadic cancers in the next century.
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页码:77 / 82
页数:6
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