MBGD: a platform for microbial comparative genomics based on the automated construction of orthologous groups

被引：62

作者：

Uchiyama, Ikuo ^{[1
]}

机构：

[1] Natl Inst Nat Sci, Natl Inst Basic Biol, Okazaki, Aichi 4448585, Japan

来源：

NUCLEIC ACIDS RESEARCH | 2007年 / 35卷

基金：

日本科学技术振兴机构; 日本学术振兴会;

关键词：

D O I：

10.1093/nar/gkl978

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The microbial genome database for comparative analysis (MBGD) is a comprehensive platform for microbial comparative genomics. The central function of MBGD is to create orthologous groups among multiple genomes from precomputed all-against-all similarity relationships using the DomClust algorithm. The database now contains > 300 published genomes and the number continues to grow. For researchers who are interested in ongoing genome projects, we have now started a new service called 'My MBGD,' which allows users to add their own genome sequences to MBGD for the purpose of identifying orthologs among both the new and the existing genomes. Furthermore, in order to make available the rapidly accumulating information on closely related genome sequences, we enhanced the interface for pairwise genome comparisons using the CGAT interface, which allows users to see nucleotide sequence alignments of non-coding as well as coding regions. MBGD is available at http://mbgd.genome.ad.jp/.

引用

页码：D343 / D346

页数：4

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