Bidirectional isotachophoresis on a planar chip with integrated conductivity detection

被引：45

作者：

Prest, JE ^{[1
]}

Baldock, SJ ^{[1
]}

Fielden, PR ^{[1
]}

Goddard, NJ ^{[1
]}

Brown, BJT ^{[1
]}

机构：

[1] UMIST, Dept Instrumentat & Analyt Sci, Manchester M60 1QD, Lancs, England

来源：

ANALYST | 2002年 / 127卷 / 11期

关键词：

D O I：

10.1039/b207462a

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The use of a miniaturised planar separation device with integrated conductivity detection for performing bidirectional isotachophoresis (ITP) is described. The chips were produced in poly( methyl methacrylate) (PMMA) using a milling procedure. To enable bidirectional ITP the devices were designed to inject samples into the centre of the separation channel and incorporated two integrated on-column conductivity detectors, positioned at opposite ends of this channel. When used with a hydrodynamic sample transport system the devices were used for the analysis of a range of small ions: NH4+; Na+; Mg2+; Ca2+; Li+; NO3-; ClO4-; SO41; F-. Results successfully achieved included the simultaneous separation of three anions and three cations.

引用

页码：1413 / 1419

页数：7