Genetics of asthma

被引：12

作者：

Blumenthal, JB

Blumenthal, MN

机构：

[1] Univ Minnesota, Asthma & Allergy Program, Dept Med, Minneapolis, MN 55455 USA

[2] Johns Hopkins Univ, Dept Med, Div Geriatr Med & Gerontol, Baltimore, MD 21205 USA

来源：

MEDICAL CLINICS OF NORTH AMERICA | 2002年 / 86卷 / 05期

关键词：

D O I：

10.1016/S0025-7125(02)00028-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Atopy and asthma seem to be related conditions involving both environmental and genetic factors, most likely consisting of multiple genes, which may interact with each other and the environment. A deeper understanding of these genetic bases and the roles that environmental factors play in the development and manifestations of these conditions will provide better methods of diagnosis and treatment.

引用

页码：937 / +

页数：15

共 55 条

[11]

Coca AF, 1923, J IMMUNOL, V8, P163

[12]

Cooke RA, 1916, J IMMUNOL, V1, P201

[13] Genetics of asthma and allergic disease [J].

Cookson, WOC ;

Moffatt, MF .

HUMAN MOLECULAR GENETICS, 2000, 9 (16) :2359-2364

[14]

COOKSON WOCM, 1989, LANCET, V1, P1292

[15] A genome-wide search for quantitative trait loci underlying asthma [J].

Daniels, SE ;

Bhattacharrya, S ;

James, A ;

Leaves, NI ;

Young, A ;

Hill, MR ;

Faux, JA ;

Ryan, GF ;

leSouef, PN ;

Lathrop, GM ;

Musk, AW ;

Cookson, WOCM .

NATURE, 1996, 383 (6597) :247-250

[16]

Deichmann KA, 1998, CLIN EXP ALLERGY, V28, P151

[17] Genome screen for asthma and related phenotypes in the French EGEA study [J].

Dizier, MH ;

Besse-Schmittler, C ;

Guilloud-Bataille, M ;

Annesi-Maesano, I ;

Boussaha, M ;

Bousquet, J ;

Charpin, D ;

Degioanni, A ;

Gormand, F ;

Grimfeld, A ;

Hochez, J ;

Hyne, G ;

Lockhart, A ;

Luillier-Lacombe, M ;

Matran, R ;

Meunier, F ;

Neukirch, F ;

Pacheco, Y ;

Parent, V ;

Paty, E ;

Pin, I ;

Pison, C ;

Scheinmann, P ;

Thobie, N ;

Vervloet, D ;

Kauffmann, F ;

Feingold, J ;

Lathrop, M ;

Demenais, F .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2000, 162 (05) :1812-1818

[18]

Dizier MH, 1999, GENET EPIDEMIOL, V16, P84, DOI 10.1002/(SICI)1098-2272(1999)16:1<84::AID-GEPI7>3.0.CO

[19]

2-D

[20] A cluster of seven tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of white children [J].

Graves, PE ;

Kabesch, M ;

Halonen, M ;

Holberg, CJ ;

Baldini, M ;

Fritzsch, C ;

Weiland, SK ;

Erickson, RP ;

von Mutius, E ;

Martinez, FD .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2000, 105 (03) :506-513

← 1 2 3 4 5 6 →