Disseminated infection with Balamuthia mandrillaris in a dog

被引:37
作者
Foreman, O [1 ]
Sykes, J [1 ]
Ball, L [1 ]
Yang, N [1 ]
De Cock, H [1 ]
机构
[1] Univ Calif Davis, Vet Med Teaching Hosp, Davis, CA 95616 USA
关键词
Balamuthia mandrillaris; brain; canine; immunohistochemistry; kidney; polymerase chain reaction;
D O I
10.1354/vp.41-5-506
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Bilateral chronic granulomatous nephritis and meningoencephalitis were diagnosed on necropsy of a 2-year-old male Great Dane dog. The causative agent was identified as Balamuthia mandrillaris, based on morphologic features, immunohistochemical staining, and deoxyribonucleic acid detection using the polymerase chain reaction with newly designed primer pairs. Trophozoite and cystic forms of the amoeba were evident within the kidneys and brain parenchyma. This is the first report on a B. mandrillaris infection in a dog.
引用
收藏
页码:506 / 510
页数:5
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