Predominance of CTX-M-type extended-spectrum β-lactamase genes among enterobacterial isolates from outpatients in Brazil

被引：31

作者：

Minarini, Luciene A. R. ^{[1
,2
,3
]}

Poirel, Laurent ^{[1
,2
]}

Trevisani, Nathalia A. C. ^{[3
]}

Darini, Ana Lucia C. ^{[3
]}

Nordmann, Patrice ^{[1
,2
]}

机构：

[1] Hop Bicetre, AP HP, INSERM Emerging Resistance Antibiot U914, Serv Bacteriol Virol,Fac Med, F-94275 Le Kremlin Bicetre, France

[2] Univ Paris 11, Le Kremlin Bicetre, France

[3] Univ Sao Paulo, Dept Anal Clin Toxicol & Bromatol, Fac Ciencias Farmaceut Ribeirao Preto, BR-14040903 Ribeirao Preto, SP, Brazil

来源：

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE | 2009年 / 65卷 / 02期

关键词：

Extended-spectrum beta-lactamases; CTX-M; Outpatients; Brazil; ESCHERICHIA-COLI; KLEBSIELLA-PNEUMONIAE; EMERGENCE; RESISTANT; REGION; CR-1; DNA;

D O I：

10.1016/j.diagmicrobio.2009.05.021

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Two hundred fifty-seven nalidixic acid-resistant enterobacterial isolates were collected in a Brazilian community from January 2000 to May 2005 to determine the prevalence of plasmid-encoded extended-spectrum beta-lactamases. The bla(CTX-M) genetic environment was determined by polymerase chain reaction and sequencing. Eleven isolates (4.2%) harbored a bla(CTX-M-2) gene, 3 isolates bla(CTX-M-9), 2 isolates bla(CTX-M-8), and 6 isolates bla(SHV-5). Two novel bla(CTX-M-2) variants, namely, bla(CTX-M-74) and bla(CTX-M-75), were identified. (C) 2009 Elsevier Inc. All rights reserved.

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页码：202 / 206

页数：5

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