Tissue attachment strength of prosthetic meshes used in ventral and incisional hernia repair - A study in the New Zealand White rabbit adhesion model

被引：34

作者：

LeBlanc, KA

Bellanger, D

Rhynes, KV

Baker, DG

Stout, RW

机构：

[1] Surg Specialty Grp, Baton Rouge, LA 70808 USA

[2] Louisiana State Univ, Dept Surg, New Orleans, LA USA

[3] Louisiana State Univ, Sch Vet Med, Div Lab Anim Med, Baton Rouge, LA 70803 USA

来源：

SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES | 2002年 / 16卷 / 11期

关键词：

hernia; ventral hernia repair; incisional hernia repair; polypropylene; polytetrafluoroethylene; rabbits; adhesions;

D O I：

10.1007/s00464-001-8271-y

中图分类号：

R61 [外科手术学];

学科分类号：

摘要：

Background: Many prosthetic materials are used in incisional hernia repair, including polypropylene (PP) and expanded polytetrafluoroethylene (ePTFE). However, PP forms severe adhesions and ePTFE has raised concerns about the adequacy of tissue attachment. Methods: The early tissue attachment strength of PP and two new forms of ePTFE (DLM and DLMC) was compared in a rabbit model (n = 12) in which disks of the three meshes (n = 8 of each material) were implanted against the abdominal wall for 3 days. Results: Tensiometer testing found that DLMC mesh had significantly greater attachment strength than PP (p = 0.02). Histologic studies indicated that this was due to cellular ingrowth. Tissue adhesions were observed with all eight PP disks, one DLMC disk, and none of the DLM disks. Conclusion: Modified forms of ePTFE mesh may provide abdominal wall repairs that are as strong or stronger than those obtained with PP, with early tissue attachment and without adhesions.

引用

页码：1542 / 1546

页数：5

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