Interactions of ruthenium coordination cubes with DNA

被引：74

作者：

Barry, Nicolas P. E. ^{[2
]}

Abd Karim, Nurul H. ^{[1
]}

Vilar, Ramon ^{[1
]}

Therrien, Bruno ^{[2
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Dept Chem, London SW7 2AZ, England

[2] Univ Neuchatel, Inst Chim, CH-2000 Neuchatel, Switzerland

来源：

DALTON TRANSACTIONS | 2009年 / 48期

关键词：

G-QUADRUPLEX-DNA; SMALL MOLECULES; DRUG DESIGN; TELOMERASE; COMPLEXES; BINDING; LIGANDS; STABILIZATION; GEOMETRY; TARGETS;

D O I：

10.1039/b913642h

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The interactions of four octacationic ruthenium coordination cubes with duplex and quadruplex (telomeric and c-myc) DNA have been studied by FID and SPR, showing these cubes to bind strongly to tetrastranded DNA structures.

引用

页码：10717 / 10719

页数：3

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