Steric vs. electrostatic effects in the nucleophilic addition to a hindered cyclohexanone

被引：4

作者：

Busch, J

Keseru, GM

Kovari, Z

Sequin, U

机构：

[1] TECH UNIV BUDAPEST,DEPT CHEM INFORMAT TECHNOL,H-1521 BUDAPEST,HUNGARY

[2] UNIV BASEL,INST ORGAN CHEM,CH-4056 BASEL,SWITZERLAND

来源：

STRUCTURAL CHEMISTRY | 1997年 / 8卷 / 04期

关键词：

cyclohexanone; nucleophilic addition; steric and electrostatic effects; molecular electrostatic potential;

D O I：

10.1007/BF02252969

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The relative importance of steric vs. electrostatic effects in the nucleophilic addition to (4R,6S)-4-(tert-butyldimethyIsiloxy)-2,2,6-trimethylcyclohexanone (1), a well-known chiral building block, is investigated.

引用

页码：257 / 261

页数：5

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