Solid-phase synthesis of aryl ethers on high loading dendrimer resin

被引：38

作者：

Basso, A

Evans, B

Pegg, N

Bradley, M ^{[1
]}

机构：

[1] Univ Southampton, Dept Chem, Southampton SO17 1BJ, Hants, England

[2] Glaxo Wellcome Res & Dev Ltd, Stevenage SG1 2NY, Herts, England

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 19期

关键词：

dendrimers; solid-phase synthesis; high-loading beads; single-bead screening;

D O I：

10.1016/S0040-4039(00)00479-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Resin-bound dendrimers have the potential to increase bead loading by at least one order of magnitude. In this letter we report the solid-phase synthesis of a library of aryl ethers using high-loading dendrimer beads, and compare the synthetic efficiency with that of TentaGel (Polystyrene-PEG) resin. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：3763 / 3767

页数：5

共 12 条

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