Trapping and storage of particles in electroactive microwells

被引：23

作者：

Cordovez, Bernardo

Psaltis, Demetri

Erickson, David ^{[1
]}

机构：

[1] Cornell Univ, Sibley Sch Mech & Aerosp Engn, Ithaca, NY 14853 USA

[2] CALTECH, Dept Elect Engn, Pasadena, CA 91125 USA

来源：

APPLIED PHYSICS LETTERS | 2007年 / 90卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1063/1.2430775

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The authors describe electroactive microwells which exploit highly localized electrokinetic effects in order to actively concentrate, confine, store, and reject particles in well defined geometries. In this letter the authors present experimental results demonstrating repeatable trapping and repulsion of polystyrene particles in wells ranging in diameter from 6 to 20 mu m in the presence of a superimposed pressure driven flow. A comprehensive finite element model is developed to describe the transport physics involved in the attraction and repulsion processes. Immediate applications include active cell trapping, particle concentration and unlabeled sensing. (c) 2007 American Institute of Physics.

引用

收藏

页数：3

相关论文

共 14 条

[1] Plastic microfluidic devices modified with polyelectrolyte multilayers [J].

Barker, SLR ;

Tarlov, MJ ;

Canavan, H ;

Hickman, JJ ;

Locascio, LE .

ANALYTICAL CHEMISTRY, 2000, 72 (20) :4899-4903

[2] A convenient apparatus to determine the zeta potential of grains by electro-osmosis [J].

Bouriat, P ;

Saulnier, P ;

Brochette, P ;

Graciaa, A ;

Lachaise, J .

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 1999, 209 (02) :445-448

[3] Integration of colloidal nanocrystals into lithographically patterned devices [J].

Cui, Y ;

Bjork, MT ;

Liddle, JA ;

Sonnichsen, C ;

Boussert, B ;

Alivisatos, AP .

NANO LETTERS, 2004, 4 (06) :1093-1098

[4] Towards numerical prototyping of labs-on-chip: modeling for integrated microfluidic devices [J].

Erickson, D .

MICROFLUIDICS AND NANOFLUIDICS, 2005, 1 (04) :301-318

[5] The path to ubiquitous and low-cost organic electronic appliances on plastic [J].

Forrest, SR .

NATURE, 2004, 428 (6986) :911-918

[6] Protein capture in silica nanotube membrane 3-D microwell arrays [J].

Kang, MC ;

Trofin, L ;

Mota, MO ;

Martin, CR .

ANALYTICAL CHEMISTRY, 2005, 77 (19) :6243-6249

[7] Cell docking inside microwells within reversibly sealed microfluidic channels for fabricating multiphenotype cell arrays [J].

Khademhosseini, A ;

Yeh, J ;

Eng, G ;

Karp, J ;

Kaji, H ;

Borenstein, J ;

Farokhzad, OC ;

Langer, R .

LAB ON A CHIP, 2005, 5 (12) :1380-1386

[8] PATTERNING SELF-ASSEMBLED MONOLAYERS - APPLICATIONS IN MATERIALS SCIENCE [J].

KUMAR, A ;

BIEBUYCK, HA ;

WHITESIDES, GM .

LANGMUIR, 1994, 10 (05) :1498-1511

[9] Pumpless, selective docking of yeast cells inside a microfluidic channel induced by receding meniscus [J].

Park, Min Cheol ;

Hur, Jae Young ;

Kwon, Keon Woo ;

Park, Sang-Hyun ;

Suh, Kahp Y. .

LAB ON A CHIP, 2006, 6 (08) :988-994

[10] Large-scale single-cell trapping and imaging using microwell arrays [J].

Rettig, JR ;

Folch, A .

ANALYTICAL CHEMISTRY, 2005, 77 (17) :5628-5634