Iridium-catalyzed conversion of alcohols into amides via oximes

被引：222

作者：

Owston, Nathan A.

Parker, Alexandra J.

Williams, Jonathan M. J.

机构：

[1] Univ Bath, Dept Chem, Bath BA2 7AY, Avon, England

[2] AstraZeneca, Proc Res & Dev, Bristol BS10 7ZE, Avon, England

来源：

ORGANIC LETTERS | 2007年 / 9卷 / 01期

关键词：

D O I：

10.1021/ol062549u

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The iridium catalyst [Ir(Cp*)Cl-2](2) is effective for the rearrangement of oximes to furnish amides. The reaction has been combined with catalytic transfer hydrogenation between an alcohol and alkene to allow the conversion of alcohols into amides in a one-pot process.

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页码：73 / 75

页数：3

相关论文

共 20 条

[1] Chelating bis-carbene rhodium(III) complexes in transfer hydrogenation of ketones and imines [J].

Albrecht, M ;

Crabtree, RH ;

Mata, J ;

Peris, E .

CHEMICAL COMMUNICATIONS, 2002, (01) :32-33

[2] N-alkylation of phenethylamine and tryptamine [J].

Cami-Kobeci, G ;

Slatford, PA ;

Whittlesey, MK ;

Williams, JMJ .

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2005, 15 (03) :535-537

[3] Conversion of alcohols into N-alkyl anilines via an indirect aza-Wittig reaction [J].

Cami-Kobeci, G ;

Williams, JMJ .

CHEMICAL COMMUNICATIONS, 2004, (09) :1072-1073

[4] Borrowing hydrogen: a catalytic route to C-C bond formation from alcohols [J].

Edwards, MG ;

Jazzar, RFR ;

Paine, BM ;

Shermer, DJ ;

Whittlesey, MK ;

Williams, JMJ ;

Edney, DD .

CHEMICAL COMMUNICATIONS, 2004, (01) :90-91

[5] Catalytic electronic activation: Indirect "Wittig" reaction of alcohols [J].

Edwards, MG ;

Williams, JMJ .

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2002, 41 (24) :4740-4743

[6]

FOOTE S, 2003, SYNTHESIS-STUTTGART, P1055

[7] CP*Ir complex-catalyzed hydrogen transfer reactions directed toward environmentally benign organic synthesis [J].

Fujita, K ;

Yamaguchi, R .

SYNLETT, 2005, (04) :560-571

[8] N-Alkylation of amines with alcohols catalyzed by a Cp*Ir complex [J].

Fujita, K ;

Li, ZZ ;

Ozeki, N ;

Yamaguchi, R .

TETRAHEDRON LETTERS, 2003, 44 (13) :2687-2690

[9] Cationic iridium complexes bearing imidazol-2-ylidene ligands as transfer hydrogenation catalysts [J].

Hillier, AC ;

Lee, HM ;

Stevens, ED ;

Nolan, SP .

ORGANOMETALLICS, 2001, 20 (20) :4246-4252

[10]

Ishihara K, 2002, ANGEW CHEM INT EDIT, V41, P2983, DOI 10.1002/1521-3773(20020816)41:16<2983::AID-ANIE2983>3.0.CO