Synthesis of chiral chromium tricarbonyl labeled thymine PNA monomers via the Ugi reaction

被引:58
作者
Baldoli, C
Maiorana, S
Licandro, E
Zinzalla, G
Perdicchia, D
机构
[1] Univ Milan, CNR, Ist Sci & Tecnol Mol, I-20133 Milan, Italy
[2] Univ Milan, Dipartimento Chim Organ, I-20133 Milan, Italy
[3] Univ Milan, CISI, Ctr Eccellenza, I-20133 Milan, Italy
关键词
D O I
10.1021/ol026994a
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
graphic Ugi condensation was used to synthesize the first examples of chiral racemic Ar.Cr(CO)(3) labeled peptide nucleic acid (PNA) monomers bearing the organometallic moiety linked to the alpha-carbon of the glycine unit.
引用
收藏
页码:4341 / 4344
页数:4
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