Mechanism of DNA strand scission induced by (1,10-phenanthroline)copper complex:: Major direct DNA cleavage is not through 1′,2′-dehydronucleotide intermediate nor β-elimination of forming ribonolactone

被引：58

作者：

Oyoshi, T ^{[1
]}

Sugiyama, H ^{[1
]}

机构：

[1] Tokyo Med & Dent Univ, Inst Biomat & Bioengn, Div Biofunct Mol, Tokyo 1010062, Japan

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2000年 / 122卷 / 26期

关键词：

D O I：

10.1021/ja9919130

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：6313 / 6314

页数：2

共 28 条

[1] REGIONS OF 23-S RIBOSOMAL-RNA PROXIMAL TO TRANSFER-RNA BOUND AT THE P-SITES AND E-SITES [J].

BULLARD, JM ;

VANWAES, MA ;

BUCKLIN, DJ ;

HILL, WE .

JOURNAL OF MOLECULAR BIOLOGY, 1995, 252 (05) :572-582

[2] Regions of 16S ribosomal RNA proximal to transfer RNA bound at the P-site of Escherichia coli ribosomes [J].

Bullard, JM ;

van Waes, MA ;

Bucklin, DJ ;

Rice, MJ ;

Hill, WE .

BIOCHEMISTRY, 1998, 37 (05) :1350-1356

[3] Model studies indicate that copper phenanthroline induces direct strand breaks via β-elimination of the 2′-deoxyribonolactone intermediate observed in enediyne mediated DNA damage [J].

Chen, TQ ;

Greenberg, MM .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (15) :3815-3816

[4] MODIFICATION OF BASES IN DNA BY COPPER ION-1,10-PHENANTHROLINE COMPLEXES [J].

DIZDAROGLU, M ;

ARUOMA, OI ;

HALLIWELL, B .

BIOCHEMISTRY, 1990, 29 (36) :8447-8451

[5] NUCLEASE ACTIVITY OF 1,10-PHENANTHROLINE COPPER-ION - CHEMISTRY OF DEOXYRIBOSE OXIDATION [J].

GOYNE, TE ;

SIGMAN, DS .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (09) :2846-2848

[6] Identification of ribosome-ligand interactions using cleavage reagents [J].

Hill, WE ;

Bucklin, DJ ;

Bullard, JM ;

Galbraith, AL ;

Jammi, NV ;

Rettberg, CC ;

Sawyer, BS ;

vanWaes, MA .

BIOCHEMISTRY AND CELL BIOLOGY, 1995, 73 (11-12) :1033-1039

[7] 2′-deoxyribonolactone lesion in DNA:: Refined solution structure determined by nuclear magnetic resonance and molecular modeling [J].

Jourdan, M ;

Garcia, J ;

Defrancq, E ;

Kotera, M ;

Lhomme, J .

BIOCHEMISTRY, 1999, 38 (13) :3985-3995

[8] DEOXYRIBONUCLEIC-ACID DAMAGE BY NEOCARZINOSTATIN CHROMOPHORE - STRAND BREAKS GENERATED BY SELECTIVE OXIDATION OF C-5' OF DEOXYRIBOSE [J].

KAPPEN, LS ;

GOLDBERG, IH .

BIOCHEMISTRY, 1983, 22 (21) :4872-4878

[9] CHEMISTRY OF NEOCARZINOSTATIN-MEDIATED DEGRADATION OF D(GCATGC) - MECHANISM OF SPONTANEOUS THYMINE RELEASE [J].

KAWABATA, H ;

TAKESHITA, H ;

FUJIWARA, T ;

SUGIYAMA, H ;

MATSUURA, T ;

SAITO, I .

TETRAHEDRON LETTERS, 1989, 30 (32) :4263-4266

[10] A highly efficient synthesis of oligodeoxyribonucleotides containing the 2′-deoxyribonolactone lesion [J].

Kotera, M ;

Bourdat, AG ;

Defrancq, E ;

Lhomme, J .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (45) :11810-11811

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