NOROVIRUS HIGHLY PREVALENT CAUSE OF ENDEMIC ACUTE DIARRHEA IN CHILDREN IN THE PERUVIAN AMAZON

被引：20

作者：

Yori, Pablo Penataro ^{[1
]}

Schwab, Kellogg ^{[2
]}

Gilman, Robert H. ^{[1
]}

Nappier, Sharon ^{[2
]}

Velasquez Portocarrero, Daniel ^{[3
]}

Black, Robert E. ^{[1
]}

Paredes Olortegui, Maribel ^{[3
]}

Hall, Eric R. ^{[5
]}

Moe, Christine ^{[4
]}

Leon, Juan ^{[6
]}

Cama, Vita A. ^{[6
]}

Kosek, Margaret ^{[1
]}

机构：

[1] Johns Hopkins Sch Publ Hlth, Dept Int Hlth, Baltimore, MD 21205 USA

[2] Johns Hopkins Sch Publ Hlth, Dept Environm Hlth Sci, Baltimore, MD 21205 USA

[3] Asocac Benef PRISMA, Lima, Peru

[4] Emory Univ, Dept Int Hlth, Atlanta, GA 30322 USA

[5] Naval Med Res Detachment, Lima, Peru

[6] Ctr Dis Control & Prevent, Div Parasit Dis, Atlanta, GA USA

来源：

PEDIATRIC INFECTIOUS DISEASE JOURNAL | 2009年 / 28卷 / 09期

基金：

美国国家卫生研究院;

关键词：

norovirus; diarrhea; calicivirus; CHI-MINH-CITY; SPORADIC GASTROENTERITIS; HUMAN CALICIVIRUSES; NORWALK VIRUS; ROTAVIRUS; INFECTIONS; ASSAY; PCR;

D O I：

10.1097/INF.0b013e3181a24730

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To determine the burden of norovirus infections in children stools from a longitudinal community cohort were evaluated using reverse transcription polymerase chain reaction. Norovirus was detected in 21.3% of diarrheal and 8.0% of nondiarrheal stools (P < 0.01). Norovirus diarrhea was highly associated with age and the odds ratio for norovirus diarrhea fell by 2.8% per month (OR = 0.97, 95% CI: 0.95-0.99). Norovirus seems to be an important etiology of community acquired diarrhea in this study population.

引用

页码：844 / 847

页数：4

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