The diversity of Rab proteins in vesicle transport

被引:673
作者
Novick, P [1 ]
Zerial, M [1 ]
机构
[1] EUROPEAN MOL BIOL LAB,D-69012 HEIDELBERG,GERMANY
关键词
D O I
10.1016/S0955-0674(97)80025-7
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Rab proteins have been primarily implicated in vesicle docking as regulators of SNARE pairing. Recent findings, however, indicate that their function in vesicle trafficking can go beyond this role, and a number of proteins, unrelated to each other, have been identified as putative Rab effectors. Although the GTPase switch of Rab proteins is highly conserved, functional mechanisms may be highly diversified among members of the Rab family.
引用
收藏
页码:496 / 504
页数:9
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