Confocal laser endomicroscopy in the "in vivo" histological diagnosis of the gastrointestinal tract

被引:89
作者
De Palma, Giovanni D. [1 ]
机构
[1] Univ Naples Federico II, Sch Med, Ctr Excellence Tech Innovat Surg, Dept Surg & Adv Technol, I-80131 Naples, Italy
关键词
Confocal microscopy; Diagnostic imaging; Gastrointestinal neoplasms; Precancerous conditions; Endoscopy; Virtual histology; SQUAMOUS-CELL CARCINOMA; FLUORESCENCE MICROSCOPY; COLORECTAL NEOPLASIA; COLLAGENOUS COLITIS; ULCERATIVE-COLITIS; BARRETTS-ESOPHAGUS; MINIPROBE; CANCER; HISTOPATHOLOGY; DISORDERS;
D O I
10.3748/wjg.15.5770
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Recent technological advances in miniaturization have allowed for a confocal scanning microscope to be integrated into a conventional flexible endoscope, or into trans-endoscopic probes, a technique now known as confocal endomicroscopy or confocal laser endomicroscopy. This newly-developed technology has enabled endoscopists to collect real-time in vivo histological images or "virtual biopsies" of the gastrointestinal mucosa during endoscopy, and has stimulated significant interest in the application of this technique in clinical gastroenterology. This review aims to evaluate the current data on the technical aspects and the utility of this new technology in clinical gastroenterology and its potential impact in the future, particularly in the screening or surveillance of gastrointestinal neoplasia. (C) 2009 The WJG Press and Baishideng. All rights reserved
引用
收藏
页码:5770 / 5775
页数:6
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