Evaluation of a hybrid pixel detector for electron microscopy

被引：42

作者：

Faruqi, AR

Cattermole, DM

Henderson, R

Mikulec, B

Raeburn, C

机构：

[1] MRC, Mol Biol Lab, Cambridge CB2 2QH, England

[2] CERN, CH-1211 Geneva 23, Switzerland

来源：

ULTRAMICROSCOPY | 2003年 / 94卷 / 3-4期

关键词：

pixel detectors; image detectors; electron microscopy;

D O I：

10.1016/S0304-3991(02)00336-4

中图分类号：

TH742 [显微镜];

学科分类号：

摘要：

We describe the application of a silicon hybrid pixel detector, containing 64 by 64 pixels, each 170 mum(2), in electron microscopy. The device offers improved resolution compared to CCDs along with faster and noiseless readout. Evaluation of the detector, carried out on a 120 kV electron microscope, demonstrates the potential of the device. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

收藏

页码：263 / 276

页数：14

相关论文

共 21 条

[1]

BARDELLONI G, 2000, P IEEE NUCL SCI S ME, P57

[2] APPLICATIONS OF A SLOW-SCAN CCD CAMERA IN PROTEIN ELECTRON CRYSTALLOGRAPHY [J].

BRINK, J ;

CHIU, W .

JOURNAL OF STRUCTURAL BIOLOGY, 1994, 113 (01) :23-34

[3] A readout chip for a 64 x 64 pixel matrix with 15-bit single Photon Counting [J].

Campbell, M ;

Heijne, EHM ;

Meddeler, G ;

Pernigotti, E ;

Snoeys, W .

IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 1998, 45 (03) :751-753

[4] Performance of a 2k CCD camera designed for electron crystallography at 400 kV [J].

Downing, KH ;

Hendrickson, FM .

ULTRAMICROSCOPY, 1999, 75 (04) :215-233

[5] ASIC-based event-driven 2D digital electron counter for TEM imaging [J].

Fan, GY ;

Datte, P ;

Beuville, E ;

Beche, JF ;

Millaud, J ;

Downing, KH ;

Burkard, FT ;

Ellisman, MH ;

Xuong, NH .

ULTRAMICROSCOPY, 1998, 70 (03) :107-113

[6] Optimization of thin-foil based phosphor screens for CCD imaging in TEM in the voltage range of 80-400 kV [J].

Fan, GY ;

Ellisman, MH .

ULTRAMICROSCOPY, 1996, 66 (1-2) :11-19

[7] Cooled CCD detector with tapered fibre optics for recording electron diffraction patterns [J].

Faruqi, AR ;

Henderson, R ;

Subramaniam, S .

ULTRAMICROSCOPY, 1999, 75 (04) :235-250

[8] Cooled CCD camera with tapered fibre optics for electron microscopy [J].

Faruqi, AR ;

Andrews, HN .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 1997, 392 (1-3) :233-236

[9] CCD detectors in high-resolution biological electron microscopy [J].

Faruqi, AR ;

Subramaniam, S .

QUARTERLY REVIEWS OF BIOPHYSICS, 2000, 33 (01) :1-27

[10] A tiled CCD detector with 2 x 2 array and tapered fibre optics for electron microscopy [J].

Faruqi, AR ;

Andrews, HN ;

Cattermole, DM ;

Stubbings, S .

NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT, 2002, 477 (1-3) :137-142