Synthesis of clustered disaccharide polyphosphate analogues of adenophostin A

被引：17

作者：

deKort, M ^{[1
]}

Valentijn, ARPM ^{[1
]}

vanderMarel, GA ^{[1
]}

vanBoom, JH ^{[1
]}

机构：

[1] LEIDEN STATE UNIV,GORLAEUS LABS,LEIDEN INST CHEM,NL-2300 RA LEIDEN,NETHERLANDS

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 43期

关键词：

D O I：

10.1016/S0040-4039(97)01811-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Three new potential ligands for the IP3 receptor (i.e. compounds 5-7) were prepared by Sonogashira coupling of propargyl 2-O-acetyl-5-O-benzyl-3-O-(3,4-di-O-acetyl-2,6-di-O-benzyl- alpha-D-glucopyranosyl)-beta-D-ribofuranoside (15) with iodobenzene, 1,2-diiodobenzene and 1,2,4,5-tetraiodobenzene, followed by deacetylation, phosphorylation and deprotection. (C) 1997 Elsevier Science Ltd.

引用

页码：7629 / 7632

页数：4

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