Simplification of the Mitsunobu reaction.: Di-p-chlorobenzyl azodicarboxylate:: A new azodicarboxylate

被引：77

作者：

Lipshutz, Bruce H. ^{[1
]}

Chung, David W. ^{[1
]}

Rich, Brian ^{[1
]}

Corral, Ricardo ^{[1
]}

机构：

[1] Univ Calif Santa Barbara, Dept Chem & Biochem, Santa Barbara, CA 93106 USA

来源：

ORGANIC LETTERS | 2006年 / 8卷 / 22期

关键词：

D O I：

10.1021/ol0618757

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Di-p-chlorobenzyl azodicarboxylate (DCAD) is introduced as a novel, stable, solid alternative to DEAD and DIAD for a variety of Mitsunobu couplings. DCAD/Ph3P-mediated reactions in CH2Cl2 generate a readily separable hydrazine byproduct.

引用

页码：5069 / 5072

页数：4

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