Toward a human epigenome

被引：47

作者：

Brena, Romulo M. ^{[1
]}

Huang, Tim H-M

Plass, Christoph

机构：

[1] Ohio State Univ, Dept Mol Genet, Div Human Canc Genet, Columbus, OH 43210 USA

[2] Ohio State Univ, Dept Mol Virol Immunol & Med Genet, Div Human Canc Genet, Columbus, OH 43210 USA

来源：

NATURE GENETICS | 2006年 / 38卷 / 12期

关键词：

D O I：

10.1038/ng1206-1359

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Sequencing of genomes, including that of humans, has revolutionized our understanding of genome organization and accelerated the hunt for disease-causing mutations. New studies by the Human Epigenome Project (HEP) now highlight the importance and complexity of cytosine DNA methylation in tissue-specific regulation of gene expression.

引用

页码：1359 / 1360

页数：2

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