An on-line quantitative immunoassay system based on a quartz crystal microbalance

被引：14

作者：

Lin, SM

Lu, CC

Chien, HF

Hsu, SM ^{[1
]}

机构：

[1] Natl Taiwan Univ, Coll Med, Off Res & Dev, Taipei 10018, Taiwan

[2] Natl Taiwan Univ, Coll Med, Ctr Optoelect Biomed, Taipei 10018, Taiwan

来源：

JOURNAL OF IMMUNOLOGICAL METHODS | 2000年 / 239卷 / 1-2期

关键词：

quartz crystal microbalance; immunoassay; polythiolation; binding ratio;

D O I：

10.1016/S0022-1759(00)00184-8

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

We have established a QCM immunoassay system which allows on-line and quantitative monitoring throughout the entire detection procedure and provides information on the surface coverage and the binding ratio of antibody to antigen. Compared to conventional immunoassay systems the QCM system offers advantages of short response times, obviates the need for additive labeling reagents, and permits direct conversion of a frequency signal into mass accumulation. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：121 / 124

页数：4

共 4 条

[1] ADDITION OF SULFHYDRYL-GROUPS TO ESCHERICHIA-COLI RIBOSOMES BY PROTEIN MODIFICATION WITH 2-IMINOTHIOLANE (METHYL 4-MERCAPTOBUTYRIMIDATE) [J].